📘 Must Know:
TIRZEPATIDE JOURNEY
Please do your own research, too!

IMPORTANT REMINDER

RECONSTITUTION GUIDE

❗ SYRINGE GUIDE

HOW TO MIX TIRZEPATIDE WITH BAC WATER

HOW TO INJECT YOUR TIRZEPATIDE

INJECTION SITES

🔬 🔥 “Plateau sa Tirz” (profiling + decision guide)May common story sa GC:● 3 months sa 5mg
● ~2 months walang bawas ang weight kahit “controlled naman”
● Nag-updose to 7.5mg
● Appetite suppression hindi na consistent> If ikaw ito, basahin muna bago sabihing “wala na effect”.
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1) Plateau at 5mg or 7.5mg ≠ immune ka naMost of the time, hindi ka desensitized.
Mas madalas ito dahil:
● Mid-dose pa lang for your body
● Weight loss is step-by-step, hindi straight line
● Appetite suppression can fade first kahit gumagana pa rin ang gamotImportant: appetite ≠ total metabolic effect.
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2) May dose ladder ang tirzepatideHindi ito gawa-gawa ng seller.
Clinical trials + FDA label support ito.Typical ladder:
2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg (max)Meaning:
● 5mg at 7.5mg = mid-ladder, hindi end game
● Marami hindi “fully on” ang effect until 10mg pataas3) Evidence-based moveSa obesity trials, may clear dose-response:
higher dose → bigger average weight loss.So kung stuck ka sa 5mg/7.5mg:
✅ Next step if tolerated
❌ Hindi agad stop o “wala na effect”4) Research peptides vs evidence-based medsIf research peptide:
● Kulang sa human trials
● Walang standard dosing
● Hindi sure ang appetite pathwayExample: AOD-9604
– May human studies
– ❌ Not effective for weight lossSS-31 / MOTS-C / AOD = support only
❌ Not main appetite driver5) About “Cagri” (cagrilintide)Different pathway (amylin).
May weight mgmt studies pero investigational pa.Think:
● Possible support
● ❌ Not automatic fix sa plateau6) “Reta is stronger?” contextRetatrutide (Reta) has human phase 2 data:
very large avg weight loss at higher doses.
Phase 3 ongoing.So if choosing next-level:
✅ Real human trial evidence
❌ Random “research-only” peptides7) Quick self-check bago sabihing “wala na effect”● Same dose, same day weekly?
● Missed / late injections?
● Weight = weekly average, not daily swings?
● Protein ok? Sleep ok? Steps ok?
● Any GI or gallbladder symptoms?🔥 Bottom lineStaying low dose for months is not always “normal”.
Most often it means stuck mid-ladder.That’s why the clinical dose ladder exists.

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